When friendship is worth more than any love. It’s the story of the inseparable young friends: Alejandra, Daniel and Omar, who live together, sharing a downtown apartment in a northern Mexican city. Due to family pressure, Alejandra is forced to give temporary shelter to a very attractive young couple they haven’t met before; Rufino and Paz. Du to an alleged family argument, the couple is on the run and need someplace to hide. At the beginning the couple appears to be very conservative regarding the friend’s lifestyle, but after a few days of sharing their living space, little by little an unusual web of desires develops among the five of them.

Raimundo Davidson is a young man in love with Florence, the niece of Dr. Belforger, master of hypnotics, who takes advantage of this faculty to intervene in a series of illegal business with his friend Burner. Aware of the fortune of Davidson, they accelerate their marriage with Florence to obtain it through the girl. Davidson is put on notice of Belforger's activities by an insurance firm. Discovered and stopped by the doctor, Davidson finally meets with Florence.

This story takes place in the middle of XIX century in Puebla, Mexico. Estela Ballesteros suffers from a heart problem. Due to this fact her family, a very preservative one, allows her to study art with the painter Octavio Durán and to have an engagement with Angel Ramirez, whom the family doesn't like. When Estela realizes that she cannot change her irresponsible fiancé, she brakes up with him and accepts to marry Octavio. On the wedding day, when Estela and Octavio are in front of the altar, Angel interrupts the ceremony to prevent the marriage, which causes that Estela has a heart attack and dies. Octavio is very affected. Angel flees to Holland where he falls in love with a dancer with whom he has a son. Daisy, the Estela's sister also dies, but before her death she leaves her daughter Estelita to Octavio, and he raises her up to be an exact copy of her aunt Estela.

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Fidel, a deaf mugger, sees the possibility of a new life after he start attending to a school for the deaf. However his chances are getting shorter as the a police officer is after his trail.

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A house is to be demolished to make a parking lot. In the process, the children of an orphanage and the old people of an asylum, both neighbors of the house, invade it secretly searching for a new place to stay. In spite of their differences in age and personality, a strange complicity arises between them, creating strong bonds of friendship.